CAS No.345909-25-3 | 6-Thioguanosine hydrate
Name:6-Thioguanosine hydrate CAS No.345909-25-3 MF:C10H13N5O4S MW:299.31 Purity:97% EINECS:201-597-2 Appearance:solid Package: 5g,25g,100g,500g,1kg,25kg Worldwide Delivery
Categories：
Biochemicals
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Product introduction
Introduction and application of CAS No.345909-25-3 | 6-Thioguanosine hydrate
2-Amino-6-mercaptopurine-9-D-riboside hydrate is a purine derivative that is used as a treatment for certain types of leukemia, such as acute lymphoblastic leukemia. It is converted to thioguanine in the body and inhibits the enzyme xanthine oxidase by forming hydrogen bonds with it. This prevents conversion of xanthine to uric acid, which results in an accumulation of uric acid in the blood. Thioguanine also inhibits the enzyme ribonucleotide reductase and reduces levels of nucleotides, which are needed for DNA synthesis. The drug has been shown to be effective when administered orally or intravenously. 2-Amino-6-mercaptopurine has been shown to possess antiinflammatory activities and can suppress immune reactions by inhibiting growth factor production by T cells.
Synonyms:
2-Amino-6-mercaptopurine-9-D-riboside hydrate;
6-Thioguanosinehydrate;
2-Amino-6-mercapto-9(.beta.-D-ribofuranosyl)purin;
2-amino-9-(3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl)-3H-purine-6-thione;
2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3H-purine-6-thione;
(-)-2-AMino-6-Mercaptopurineribosidehydrate98%;
2-(2-amino-6-mercapto-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;
9H-Purine-6-thiol,2-amino-9-.beta.-D-xylofuranosyl-,monohydrate;
2-amino-9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purine-6-thione
Specification of CAS No.345909-25-3 | 6-Thioguanosine hydrate
|
ITEMS |
SPECIFICATION |
|
CAS |
345909-25-3 |
|
MF |
C10H13N5O4S |
|
MW |
299.31 |
|
Melting point |
230-231 °C (dec.)(lit.) |
Package and transportation of Introduction and application of CAS No.345909-25-3 | 6-Thioguanosine hydrate
Package:100g; 500g; 1kg; 25kg;bulk package
Transportation: by courier/ by air/ by sea
Related Articles of CAS No.345909-25-3 | 6-Thioguanosine hydrate
Structural Characterization of 6-Thioguanosine and Its Monohydrate in the Gas Phase
H Saigusa, A Oyama, S Kitamura… - The Journal of Physical …, 2021 - ACS Publications
… Detailed structural analysis of 6-thioguanosine (6TGs) in relation to its tautomerization and
… It is demonstrated that hydration behavior of 6TGs is significantly different from that of Gs as …
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